A cikin ruwan 'ya'yan itace na ciki na mutum, BPC 157 yana da kwanciyar hankali fiye da sa'o'i 24, don haka yana da kyakkyawan bioavailability na baka (ko da yaushe ana ba da shi kadai) da kuma tasiri masu amfani a cikin dukan gastrointestinal tract.Wannan wani muhimmin bambanci ne daga sauran peptides masu inganci, waɗanda ke dogara da aikin da ƙari mai ɗaukar kaya ko kuma an lalata su da sauri a cikin ruwan 'ya'yan itace na ciki na ɗan adam.Saboda haka, barga BPC 157 ana ba da shawarar zama matsakanci na cytoprotection na Robert, wanda ke kiyaye mutuncin mucosa na ciki na ciki.Muna ba da shawarar cewa gudummawar BPC 157 zuwa cytoprotection na Robert - wato, ikon magance cututtukan cututtukan ciki na asali na barasa, wanda Robert ya kira cytoprotection - da kuma ikon magance raunin da ya taso daga mummunan hulɗar kai tsaye na wakili mai cutarwa tare da tantanin halitta. wakiltar haɗin kai tsakanin gut da axis na kwakwalwa.
Perovic ya ruwaito cewa BPC 157 yana da tasiri mai tasiri na warkewa dangane da dawo da berayen tare da raunin kashin baya tare da gurguntaccen wutsiya (rauni na minti 1 na matsawa na kashin baya na sacrocaudal [S2-Co1]).Musamman, gudanarwar intraperitoneal BPC 157 guda ɗaya a cikin mintuna 10 bayan raunin da ya faru yana magance mummunan tasirin.Sabanin haka, raunin kashin baya da ciwon wutsiya na ci gaba a cikin berayen da ba a kula da su ba, kwanakin da aka tantance, makonni, watanni, da shekara guda bayan raunin.Na bayanin kula, BPC 157 yana rage lalacewar da aka saba haifarwa.Ta haka, BPC 157 far yana haifar da bayyanannen aiki, microscopic, da farfadowa na electrophysiologic.
Abin lura, a cikin berayen da ke da rauni na kashin baya, akwai sake dawowa na dindindin.Da zarar an gudanar da BPC 157 a cikin mintuna 10 bayan rauni na matsawa, ana samun ci gaba da kariya kuma babu wata matsala ta kashin baya da ta haifar da tashe-tashen hankula da ke sake bayyana.
Don haka, ana iya tunanin cewa farkon hemostasis na iya zama da fa'ida kuma yana ba da damar dawo da aiki bayan raunin kashin baya a cikin berayen.Duk da haka, tasirin da BPC 157 ke yi yana iya bambanta da sauƙi mai sauƙi na hemostatic wanda zai rage raunin kashin baya, saboda BPC 157 kuma yana inganta aikin thrombocyte a cikin berayen ba tare da rinjayar abubuwan haɗin gwiwa ba.Yayin murmurewa daga raunin kashin baya, BPC 157 shima yana kare endothelium kai tsaye, yana rage rikicewar rikicewar jijiyoyin jijiyoyin jiki, da sauri yana kunna madadin hanyoyin wucewa, kuma yana magance cututtukan venous occlusion.Don haka, ana ɗauka cewa akwai gagarumar gudunmawar venous ga matsawa na kashin baya, ana iya tunanin cewa sake kafa jinin da aka yi ta hanyar BPC 157 na iya ba da gudummawa ga saurin farfadowa.Bugu da ƙari kuma, la'akari da cewa BPC 157 yana inganta farfadowa na dindindin bayan matsawa na kashin baya, ya kamata a lura cewa lokacin da aka ba da BPC 157 a lokacin sake sakewa, yana magance bugun jini wanda ya haifar da haɗin gwiwa na carotid arteries na kowa.BPC 157 yana warware lalacewar neuronal kuma yana hana ƙwaƙwalwar ajiya, locomotor, da gazawar daidaitawa.BPC 157 a fili yana aiwatar da waɗannan tasirin ta hanyar canza yanayin magana a cikin hippocampus.
A ƙarshe, BPC 157 yana yin tasiri mai amfani akan bugun jini, schizophrenia, da raunin kashin baya.
Masu bincike sun nuna akai-akai cewa BPC 157 yana yin tasiri mai yawa a cikin jiki.Babu wani dalili da zai nuna cewa fa'idodin BPC 157 an iyakance su ta ingancin samfuran da aka yi amfani da su da/ko iyakokin hanyoyin.Tabbas, zamu iya jayayya cewa tasiri, sauƙin amfani, amintaccen bayanan asibiti da tsarin BPC 157 suna wakiltar madadin, mai yiwuwa nasara, jagorar warkewa na gaba don yanayin jijiya.Sabili da haka, ana buƙatar ƙarin karatu don fayyace yadda yuwuwar maganin BPC 157 zai iya yin mu'amala ta musamman tare da tsarin aikin da ya ƙunshi rukunin ƙananan ƙwayoyin cuta da yawa a cikin CNS.Ya kamata a bincika tasirin tasirin mafi yawan, idan ba duka ba, tsarin neuronal a cikin kwayoyin halitta, salon salula, da matakan tsarin.Wasu visceral relay relay na CNS ko gabobin dawafi, ɗaya daga cikin ƴan yankuna a cikin kwakwalwa ba tare da shingen kwakwalwar jini ba, sanannen hanya ce wacce peptide da aka sarrafa ta tsarin zai iya yin tasiri ta tsakiya.Don haka, dole ne ta yi aiki a cikin gaɓar gut-kwakwalwa, ko da kuwa ko wannan aikin kai tsaye ne ko kai tsaye.
